Giants vs. Seahawks prediction: NFL Week 5 odds, picks, best bets Sunday

Seattle had its three-game winning streak snapped by Detroit last week in a hard-fought road game between two of the better teams in the NFC. The Seahawks continued to look strong on offense, accumulating 516 total yards.However, due to a laundry list of inactive players, the defense struggled, surrendering 42 points on six touchdowns to five different players.Meanwhile, the underdog Giants hit the road without one of their top offensive producers and another is doubtful.Here is our preview of Sunday’s Giants vs.

Seahawks matchup (4:25 p.m.ET, CBS) with betting odds, a prediction and a pick.Seattle’s Lumen Field is one of the toughest venues and environments for road teams to win at, so the Giants have their work cut out as they also deal with crossing three time zones for this game.

They’re also facing a team with the highest-graded rushing offense, per Pro Football Focus.That’s a bad matchup for the Giants, who are ranked 20th in run defense grade and are allowing the ninth-most yards per rush attempt in the NFL.The G-Men’s saving grace is its red-zone defense, which has allowed opponents to score touchdowns in only 25% of their trips over the past three weeks (second in NFL). However, Seattle has been surgical, particularly at home, in red-zone scoring, punching it in 67% of the time (No.

7 in NFL).Last week against Detroit, the Seahawks scored on three of their four trips inside the red zone (INT), with another touchdown coming on a run by Kenneth Walker just outside the Lions’ 20.Making matters worse for the Giants, the Seahawks are expected to get several key defensive players back that were missing from last week’s loss. LB Jerome Baker, DL Leonard Williams, OLBs Boye Mafe and Uchenna Nwosu and first-rounder DT Byron Murphy II all missed Seattle’s “Monday Night Football” matchup against Detroit.

Baker, Williams and Nwosu have a good chance to return this week, giving Seattle a better shot at stuffing the Giants’ run game, which wa...