Christina Applegate Reveals She Faced 'First Sign Of MS' While Filming 'Dead To Me' Pilot

LOADINGERROR LOADINGMore than three years after going public with her multiple sclerosis diagnosis, Christina Applegate continues to reflect on her earliest experiences with the disease.On Tuesday’s episode of her “MeSsy” podcast, the actor recalled experiencing one of the first symptoms of multiple sclerosis, or MS, while filming the pilot episode of the smash Netflix series “Dead to Me.” Advertisement In conversation with “Dead to Me” creator Liz Feldman, Applegate discussed a scene from the episode that required her to run across a field, saying, “I remember falling that day.

Hi, first signs of MS!”Feldman, meanwhile, assumed the actor was just fatigued due to the series’ rigorous shooting schedule.“I remember you losing your balance a couple of times, but it was very hard to figure out,” she said.

“I remember one time it was like really late at night, we’d been shooting probably 14 or 15 hours, it seemed completely reasonable that anybody would be collapsing.”Advertisement “It was MS,” Applegate clarified.Liz Feldman, center, with "Dead to Me" actors Christina Applegate and Linda Cardellini in 2019.Applegate recently shared how her earliest experiences with multiple sclerosis occurred while filming the series.Leon Bennett via Getty Images“Dead to Me,” which aired from 2019 to 2022, follows Jen Harding (Applegate), a California widow who strikes up a close friendship with Judy Hale (Linda Cardellini), who is purportedly mourning the death of her fiancé, in a grief support group.

As details about the death of Jen’s husband emerge, however, the two women’s lives become entangled in darkly comedic ways.Applegate announced she’d been diagnosed with MS in August 2021.

The disease attacks the central nervous system and impairs communication between the body and the brain, with symptoms including tremors, fatigue, vision loss, slurred speech and weakness in the limbs.Advertisement Production on the third se...